Indocyanine green (ICG) for the detection of sentinel lymph nodes in patients with endometrial cancer

Zaur N. Ibragimov; Ибрагимов Заур Намигович; Nikolay A. Mikaya; Микая Николай Александрович; Yuri N. Trifanov; Трифанов Юрий Николаевич; Tatiana V. Gorodnova; Городнова Татьяна Васильевна; Khristina B. Kotiv; Котив Христина Богдановна; Maria G. Yakovleva; Яковлева Мария Георгиевна; Olga E. Lavrinovich; Лавринович Ольга Евгеньевна; Nikolay E. Bondarev; Бондарев Николай Эдуардович; Anna A. Sidoruk; Сидорук Анна Александровна; Olga A. Smirnova; Смирнова Ольга Алексеевна; Konstantin Dz. Guseinov; Гусейнов Константин Джамилиевич; Elena V. Bakhidze; Бахидзе Елена Вилльевна; Iryna E. Meshkova; Мешкова Ирина Евгеньевна; Elvina K. Bakaeva; Бакаева Эльвина Хисматуловна; Marianna G. Shikhzadaeva; Шихзадаева Марианна Гульмугамедовна; Elena A. Ul’rikh; Ульрих Елена Александровна; Adel F. Urmancheeva; Урманчеева Адель Федоровна; Igor V. Berlev; Берлев Игорь Викторович; Alexey M. Belyaev; Беляев Алексей Михайлович

doi:10.18565/aig.2020.1suppl.105-111

Indocyanine green (ICG) for the detection of sentinel lymph nodes in patients with endometrial cancer

Authors: Ibragimov Z.N.¹, Mikaya N.A.¹, Trifanov Y.N.¹, Gorodnova T.V.¹, Kotiv K.B.¹, Yakovleva M.G.¹, Lavrinovich O.E.¹, Bondarev N.E.¹, Sidoruk A.A.¹, Smirnova O.A.¹, Guseinov K.D.¹, Bakhidze E.V.¹, Meshkova I.E.¹, Bakaeva E.K.¹, Shikhzadaeva M.G.¹, Ul’rikh E.A.¹, Urmancheeva A.F.¹, Berlev I.V.¹, Belyaev A.M.¹
Affiliations:
1. Petrov National Medical Research Center of Oncology of Minzdrav of Russia
Issue: No 1S (2020): Supplement
Pages: 105-111
Section: Articles
URL: https://journals.eco-vector.com/0300-9092/article/view/248789
DOI: https://doi.org/10.18565/aig.2020.1suppl.105-111
ID: 248789

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Abstract

Aim. To investigate the effectiveness of the ICG fluorescence technique in the detection of sentinel lymph nodes (SLN) in patients with endometrial cancer (EC). Materials and methods. The study comprised 100 patients with morphologically and clinically verified stage T1a-1bNxM0 EC, who were managed at the Petrov National Medical Research Center of Oncology of Minzdrav of Russia from September 2015 to September 2017. Results. The use of ICG resulted in the detection of220 SLNs in the whole study cohort (n = 100). Ninety (90%) patients were found to have bilateral SLNs. In 9/100 (9%), staining was detected only on one side. Only in one case, no SLNs were identified. The sensitivity, specificity, and accuracy of the method were 100%, 93%, and 93%, respectively. Numerous studies confirm the fact that in patients with EC, intraoperative detection, biopsy and morphological examination of SLNs contribute to a better assessment of regional lymphatic collectors, more accurate staging of the disease, and a patient-tailored surgery, which in turn can increase the overall survival of patients with EC. Conclusion. The use of the ICG fluorescence technique for the detection of SLNs in patients with EC allows effective and safe staging of the disease.

Keywords

ICG, corpus uteri cancer, sentinel lymph node, ICG, fluorescence

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Indocyanine green (ICG) for the detection of sentinel lymph nodes in patients with endometrial cancer

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