HAIR AS OBJECT OF CHEMICAL AND TOXICOLOGICAL ANALYSIS

Мұқаба

Дәйексөз келтіру

Толық мәтін

Аннотация

Lately there is an increasing interest in forensic and clinical toxicology to detect drugs and psychotropic substances in hair samples. This biological object extends opportunity to detect drugs and other toxic substances in the human body. The main difficulty in investigating the hair is a correct selection of sample preparation conditions of the object subject to chemical and toxicological studies in order to obtain a more complete extraction of toxins from the inside of the hair. For this purpose the following methods are applied: organic solvent-based extraction; organic solvent-based extraction at lower temperatures; thermal decomposition of objects; alkaline or acidic hydrolysis followed by mixed solvents-based liquid-liquid extraction; methanol-based extraction or acidified methanol-based extraction in an utrasonic bath; enzymatic hydrolysis followed by mixed solvents-based liquid-liquid extraction.

Авторлар туралы

Julija Slustovskaia

St. Petersburg State Chemical-Pharmaceutical Academy

Хат алмасуға жауапты Автор.
Email: noemail@neicon.ru

Аспирант кафедры фармацевтической химии ГБОУ ВПО «Санкт-Петербургская химико-фармацевтическая академия» Министерства здравоохранения РФ, 197376, г. Санкт-Петербург, Российская Федерация

e-mail: yulia8356@yandex.ru

Ресей

Ol’ga Strelova

St. Petersburg State Chemical-Pharmaceutical Academy

Email: noemail@neicon.ru

Кандидат химических наук, доцент, заведующая кафедрой фармацевтической химии ГБОУ ВПО «Санкт-Петербургская химико-фармацевтическая академия» Министерства здравоохранения РФ, 197376, г. Санкт-Петербург, Российская Федерация

e-mail: ous.chim-tox@yandex.ru

Ресей

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© Slustovskaia J.V., Strelova O.J., 2015


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