CONCERNING COORDINATION BETWEEN THE GENERALLY ACCEPTED PRACTICE OF ASSESSING HEALTH RISKS DUE TO MULTI-METALLIC EXPOSURES AND THE THEORY OF COMBINED TOXICITY

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Assessment of cumulative health risks associated with the widely observed combined effects of two or more metals and their compounds to the organism has the toxicology of mixtures as its scientific basis although there is no full match between such assessment and this basis though some of the contradictions between them are of a fundamental nature. This state of things may be explained not only by simplifications characteristic of the generally recognized methodology of risk assessment but also by extreme complexity of the theory of combined toxicity, the most essential issues of which are considered by authors on the basis of literary and, mostly, their own previously published data.

Sobre autores

I. Minigalieva

The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers of Rospotrebnadzor

Autor responsável pela correspondência
Email: noemail@neicon.ru
Rússia

B. Katsnelson

The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers of Rospotrebnadzor

Email: noemail@neicon.ru
Rússia

V. Gurvich

The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers of Rospotrebnadzor

Email: noemail@neicon.ru
Rússia

L. Privalova

The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers of Rospotrebnadzor

Email: noemail@neicon.ru
Rússia

V. Panov

Institute of Industrial Ecology, the Ural Branch of the Russian Academy of Sciences

Email: noemail@neicon.ru
Rússia

A. Varaksin

Institute of Industrial Ecology, the Ural Branch of the Russian Academy of Sciences

Email: noemail@neicon.ru
Rússia

M. Sutunkova

The Medical Research Center for Prophylaxis and Health Protection in Industrial Workers of Rospotrebnadzor

Email: noemail@neicon.ru
Rússia

Bibliografia

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  15. Minigaliyeva I.A., Katsnelson B.A., Panov V.G., Privalova L.I., Varaksin A.N., Gurvich V.B., Sutunkova M.P., Shur V.Ya., Shishkina E.V., Valamina I.E., Zubarev I.V., Makeyev O.H., Meshtcheryakova E.Y., Klinova S.V. In vivo toxicity of copper oxide, lead oxide and zinc oxide nanoparticles acting in different combinations and its attenuation with a complex of innocuous bio-protectors. Toxicology. 2017; 380: 72-93.
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Declaração de direitos autorais © Minigalieva I.A., Katsnelson B.A., Gurvich V.B., Privalova L.I., Panov V.G., Varaksin A.N., Sutunkova M.P., 2017


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