CHRONIC INTOXICATION WITH ETHANOL: METABOLIC CHANGES, CORRECTION OF DISTURBANCES

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In experimental animals with 30-day and to a greater extent 60-day ethanol intoxication, the development of toxic lesion of the liver, «oxidative stress», disturbances of functional and metabolic activity of erythrocytes and neutrophils in peripheral blood was established. The application of a combination of immune modulator (longidaza), antioxidant (mexicor) and membrane protector (essentiale forte H) completely corrects metabolic disturbances at 30-day ethanol intoxication and partially at 60-day ethanol intoxication.

作者简介

Aleksandr Konoplya

Kursk State Medical University, Ministry of Health of the Russian Federation

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Доктор мед. наук, проф., заслуженный деятель науки РФ, зав. кафедрой биологической химии Курского государственного медицинского университета Министерства здравоохранения Российской Федерации, 305041, г. Курск, Российская Федерация

e-mail: konoplya51@mail.ru

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Alexey Loktionov

Kursk State Medical University, Ministry of Health of the Russian Federation

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Доктор мед. наук, доц. кафедры хирургических болезней №2 Курского государственного медицинского университета Министерства здравоохранения Российской Федерации, 305041, г. Курск, Российская Федерация

e-mail: ala-loc@yandex.ru

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Valentin Dudka

Kursk State Medical University, Ministry of Health of the Russian Federation

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Ассистент кафедры фармакологии Курского государственного медицинского университета Министерства здравоохранения Российской Федерации, 305041, г. Курск, Российская Федерация

e-mail: dudkaviktor@rambler.ru

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Svetlana Dolgareva

Kursk State Medical University, Ministry of Health of the Russian Federation

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Доктор мед. наук, проф. кафедры биологической химии Курского государственного медицинского университета Министерства здравоохранения Российской Федерации, 305041, г. Курск, Российская Федерация

e-mail: ala-loc@yandex.ru

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Aleksandr Sorokin

Kursk State Medical University, Ministry of Health of the Russian Federation

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Студент 6 курса лечебного факультета Курского государственного медицинского университета Министерства здравоохранения Российской Федерации, 305041, г. Курск, Российская Федерация

 e-mail: vfts@mail.ru

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Olga Bushmina

Kursk State Medical University, Ministry of Health of the Russian Federation

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Ассистент кафедры биологической химии Курского государственного медицинского университета Министерства здравоохранения Российской Федерации, 305041, г. Курск, Российская Федерация

e-mail: bushminaon@kursksmu.net

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参考

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版权所有 © Konoplya A.I., Loktionov A.L., Dudka V.V., Dolgareva S.A., Sorokin A.V., Bushmina O.N., 2015


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