SULFONYLUREAS IN THE TREATMENT OF TYPE 2 DIABETES MELLITUS TODAY. IS THERE A PROSPECT?


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Abstract

Despite significant advances in the study of the pathophysiology of type 2 diabetes mellitus and numerous publications in its treatment, there is a large gap between well-established recommendations for its treatment and authentically known remote results of long-term use of drugs. The article analyzes the results of numerous studies on the efficacy and safety of different groups of antihyperglycemic drugs and their comparisons, as well as algorithms for their administration. Common point of view, however, has not yet developed. In all diabetes congresses and in the literature different recommendations are discussed, but the issue of positioning of certain drugs is still open.

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