Hygienic standardization of 2-formylphenoxyethane acid in the air of the working zone

The toxic properties of 2-formylphenoxyethane acid for hygienic standardization in the air of working zone were studied. The substance in the dose equal of DL₅₀ introduced into the stomach for male rats, male and female mice accounted for 5354, 3698 and 4322 mg/kg. It refers to moderately hazardous substances. No significant differences in species and gender sensitivity of animals to the substance were noted. It possesses a strong ability to cumulation: C_сит is 2.9. It has a marked irritating effect to the mucous membranes of eyes and the moderate one - to the skin. Ithas a toxic effect on the liver, kidneys, central nervous system. The threshold of acute inhalation effect (Lim_ас) is 120.3 mg/m³. At Lim_ас level it has no irritating effect on the respiratory tract. The tentative safe exposure level of 2-formylphenoxyethane acid in the air of working zone is 1 mg/m³.

2-формилфеноксиэтановая кислота, токсикологическая характеристика, гигиеническое нормирование, 2-formylphenoxyethane acid, toxicological characteristics, hygienic standardization