电邮这篇文章 ASSESSMENT OF TOXICITY AND HAZARD OF TECHNICAL PRODUCT OF TRIAZINONE’S DERIVATIVE
- 作者: Rakitskii V.N.1, Еpishina T.M.1, Chkhvirkiya E.G.1, Sinitskaya TA.1, Mukhina Е.A.2
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隶属关系:
- F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
- .F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
- 期: 编号 1 (2019)
- 页面: 39-42
- 栏目: Articles
- ##submission.datePublished##: 28.02.2019
- URL: https://vestnik.nvsu.ru/0869-7922/article/view/641151
- DOI: https://doi.org/10.36946/0869-7922-2019-1-39-42
- ID: 641151
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详细
Experimental assessment of toxicity and hazard of technical product of triazinone’s derivative at its peroral administration into warm-blooded animals’ bodies (male rats) has been conducted to determine the character of the substance biological action. Its acute peroral toxicity was at the level of LD50 -1693 ± 470 mg/kg of body weight, hazard class – 4 according to Hygienic Classification of Pesticides (Sanitary Rules & Standards 1.2.2584-10). Effective dose was 62.5 mg/kg b.w., non-effective dose (NOEL) was 12.5 mg/kg b.w. ADI was 0.1 mg/kg b.w.
作者简介
V. Rakitskii
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
编辑信件的主要联系方式.
Email: pesticidi@yandex.ru
Rakitskii Valery Nikolaevich
141014, Mytishchi, Moscow Region,
俄罗斯联邦T. Еpishina
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Email: pesticidi@yandex.ru
Epishina Tatiana Mihailovna
141014, Mytishchi, Moscow Region,
俄罗斯联邦E. Chkhvirkiya
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Email: pesticidi@yandex.ru
Chkhvirkiya Elena Grigor'evna
141014, Mytishchi, Moscow Region,
俄罗斯联邦T Sinitskaya
F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Email: pesticidi@yandex.ru
Sinitskaya Tat'yana Alekseevna
141014, Mytishchi, Moscow Region,
俄罗斯联邦Е. Mukhina
.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor
Email: pesticidi@yandex.ru
Mukhina Ekaterina Aleksandrovna
141014, Mytishchi, Moscow Region,
俄罗斯联邦参考
- Rakitskii V.N. Hygienic principles and criteria of pesticide danger (risk) assessment. In:Collection of Studies: Hygienic Aspects of Environment and Public Health Protection. Sbornik nauchnykh trudov: Gigienicheskie aspekty okhrany okruzhayushchry sredy I zdoron’ya naseleniya. Moscow;1999.(in Russian)
- Sinitskaya T.A., Malinovskaya H.H.Toxicological-hygienic justification of the acceptable daily intake of acetamiprid. М. Gigiena and sanitariy. 2016; 95(11):1055-1058.
- Methodical instruction on hygienic assessment of new pesticides. Kiev. 1988; 210 p.
- Kagan Y.S. General pesticide toxicology. – Kiev. Zdorovie. 1981; 176 р.
- Rylova M.L. Method of exploring chronic action of adverse environment factors in theexperiment. L., Medicine.1964; 227 р.
- Pavlenko S.M. Application of summation-threshold index in toxicological experiment on white rats. Methodic of sanitary-toxicological experiment: scientific works collections of MNIIG named after F.F.Erisman. M. 1975; 5-
- Methodical recommendation on using reaction of animals’ behaviour in toxicological researches for hygienic standartization. Kiev. 1980; 47 p.
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- Clinical biochemistry: Manual for laboratory doctors. Kalb V.G., Kamyshnikov V.S. Minsk, Byelorussia. 1976; 311p.
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