Formation, development and activities of the Department of Clinical Toxicology of the Russian Medical Academy of Continuous Professional Education
- Authors: Gol′dfarb Y.S.1,2, Kabanova S.A.2, Lezhenina N.F.1,3, Potskhveriya M.M.1,2, Ostapenko Y.N.1,2,3, Sleptsov V.I.2
-
Affiliations:
- Russian Medical Academy of Continuous Professional Education, RF Ministry of Health
- Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
- Scientific and Practical Toxicological Center of the Federal Medical and Biological Agency
- Issue: No 2 (2021)
- Pages: 2-13
- Section: Articles
- Published: 04.05.2021
- URL: https://vestnik.nvsu.ru/0869-7922/article/view/641277
- DOI: https://doi.org/10.36946/0869-7922-2021-2-2-13
- ID: 641277
Cite item
Full Text
Abstract
The creation of an emergency clinical toxicology service in our country led to the need to train clinical toxicologists and to create a specialized Department for this purpose, which was opened in 1985 at the Central Institute of Advanced Medical Training. The staff of the Department carried out a lot of methodological, educational and scientific work, which allowed to achieve a high level of teaching. Successful activity of the Department was promoted by: work on the clinical basis of a multidisciplinary research medical institution – N.V. Sklifosovsky Research Institute for Emergency Medicine; admission to the Institute a large number of patients with various intoxications ensuring thematic completeness of teaching; the unity of command in the leadership of the Toxicological Department of the N.V. Sklifosovsky Research Institute for Emergency Medicine and the Department of Clinical Toxicology of the Russian Medical Academy of Continuous Professional Education in the person of E.A. Luzhnikov, who used his experience in scientific, practical and teaching activities of the Department; due to the existence of the scientific school of academician E.A. Luzhnikov – the development of new technologies for screening, treatment and rehabilitation of acute poisonings; the use of modern teaching methods, including field cycles and distance learning technologies; close interaction with scientific societies, contributing to a significant expansion of the possibilities of new teaching methods.
About the authors
Yu. S. Gol′dfarb
Russian Medical Academy of Continuous Professional Education, RF Ministry of Health; Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
Author for correspondence.
Email: goldfarb@mail.ru
Gol′dfarb Yuriy Semenovich
125993, Moscow
129090, Moscow
S. A. Kabanova
Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
Email: kabanovasklif@mail.ru
Kabanova Svetlana Aleksandrovna
129090, Moscow
Russian FederationN. F. Lezhenina
Russian Medical Academy of Continuous Professional Education, RF Ministry of Health; Scientific and Practical Toxicological Center of the Federal Medical and Biological Agency
Email: natalilezhenina@rambler.ru
Lezhenina Natalya Fedorovna
125993, Moscow
Russian FederationM. M. Potskhveriya
Russian Medical Academy of Continuous Professional Education, RF Ministry of Health; Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
Email: potskhveriya@mail.ru
Potskhveriya Mikhail Mikhailovich
125993, Moscow
129090, Moscow
Yu. N. Ostapenko
Russian Medical Academy of Continuous Professional Education, RF Ministry of Health; Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department; Scientific and Practical Toxicological Center of the Federal Medical and Biological Agency
Email: rtiac@mail.ru
Ostapenko Yuriy Nikolaevich
125993, Moscow
129090, Moscow
V. I. Sleptsov
Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
Email: SlepcovVI@sklif.mos.ru
Sleptsov Vasiliy Ivanovich
129090, Moscow
Russian FederationReferences
- Khubutiya M.Sh., Gol′dfarb Yu.S., Kabanova S.A., Bogopol′sky P.M. Clinical toxicology in Russia. Historical aspects. Moscow: Medpraktika-M; 2017 (in Russian).
- Gol′dfarb Yu.S., Kabanova S.A., Sleptsov V.I., Petrikov S.S., Ostapenko Yu.N., Potskhveriya M.M. Creation of Foundations for Emergency Clinical Toxicology Service in Russia. Russian Sklifosovsky Journal Emergency Medical Care. 2020; 9(3): 468–483 (in Russian). https://doi.org/10.23934/2223-90222020-9-3-468-483.
- Luzhnikov E.A. Clinical toxicology: textbook. Moscow: Meditsina; 1982 (in Russian).
- Luzhnikov E.A., Sukhodolova G.N. Clinical toxicology: textbook. 4th ed., reprint. and supplement. M.: LLC “Medical Information Agency”; 2008 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S., Ostapenko Yu.N., Sukhodolova G.N. Modern achievements in clinical toxicology and postgraduate education. In: Postgraduate medical education at the present stage. Moscow: Publishing house M-Vesti; 2000:146-152 (in Russian).
- Luzhnikov E.A., Novikovskaya T.V., Lisovik Zh.A. Search for specific therapy in acute dichloroethane poisoning. Occupational medicine and industrial ecology. 1989; (6): 37–38 (in Russian).
- Luzhnikov E.A., Ilyashenko K.K., Gol′dfarb Yu.S., Epifanova N.M., Sukhodolova G.N., Ostapenko Yu.N., etc. Clinic, diagnosis and treatment of acute poisoning with leponex and finlepsin. Department of Health, 2004 (in Russian).
- Luzhnikov E.A., Savina A.S., Galankina I.E. Toxic heart damage in acute poisoning of chemical etiology. Cardiology, 1986; 5:5-11 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S., Lezhenina N.F., Ilyashenko K.K., Sukhodolova G.N., Petrov S.I., etc. Diagnosis and treatment of toxic-hypoxic encephalopathy in cases of poisoning with psychotropic substances: methodic. recommendations No. 20. Moscow: Department of Health, 2006 (in Russian).
- Lezhenina N.F., Luzhnikov E.A. Clinical efficiency of apizol in toxic hypoxic encephalopathy. Trace elements in medicine. 2010; 11(1):57–60 (in Russian).
- Kovalenko L.A., Luzhnikov E.A., Sukhodolova G.N., Badalyan A.V. Comparative assessment of the functional state of the central nervous and respiratory systems in the toxicogenic phase of acute barbiturate poisoning in children and adults. In: Effectiveness of the state and organization of the toxicological service of the Ural Federal District in improving the provision of assistance to patients with acute poisoning: collection of works of the second scientific conference. UFD on clinical toxicology with internat. participation (Yekaterinburg, September 19-20, 2013). Yekaterinburg: UGMU Publishing House, 2013:125-129 (in Russian).
- Volkov S.V., Ermolov A.S., Luzhnikov E.A. Chemical burns of the esophagus and stomach (endoscopy, diagnostics and laser therapy). M.: Medpraktika-M, 2005 (in Russian).
- Simanko I.I., Musselius S.G. Acute renal and hepatic failure. – M.: Medicine, 1993 (in Russian).
- Vavilov M.P., Vorotyntsev P.A., Luzhnikov E.A., Nazarova E.K. Nonspecific leucocytosis in vitro as a test of the comparative cytotoxicity of low-molecularelectrolytes. Bulletin of Experimental Biology and Medicine. 1995; (2): 174176 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S., Marupov A.M. Endotoxicosis in acute exogenous poisoning. Moscow: BINOM; 2008 (in Russian).
- Lezhenina N.F., Luzhnikov E.A., Ermokhina T.V., Borovkova N.V., Lisovik Zh.A., El′kov A.N. Significance of immunological parameters in the diagnosis of toxic hypoxic encephalopathy in acute poisoning with neurotoxic substances. Toxicological Review. 2009; 1(94):8-11 (in Russian).
- Dagaev V.N., Iskandarov A.I., Luzhnikov E.A., Gorin E.E., Lisovik Zh.A. Expert criteria for the severity of chemical trauma in acute poisoning FOI. Court. medical expertise. 1990; (1): 16-17 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S., Musselius S.G. Detoxification therapy (manual). Saint Petersburg: Lan; 2000 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S. Physiohemotherapy of acute poisoning. M.: Medpraktika-M; 2002 (in Russian).
- Petrov S.I. Use of sodium hypochlorite in the complex treatment of acute poisoning with amitriptyline. Toxicological Review. 2003; (3): 29-34 (in Russian).
- Matkevich V.A. Comparative evaluation of the effectiveness of methods of enteral detoxification of the body on the example of acute oral poisoning with amitriptyline. Toxicological Review. 2007; (2): 29-34 (in Russian).
- Matkevich V.A., Lisovik Zh.A., Luzhnikov E.A., Alexandrovsky V.N. Toxicokinetics of organophosphorus insecticides in acute oral poisoning and rational detoxification tactics. Toxicological Review. 2010; (6): 6–10 (in Russian).
- Matkevich V.A., Luzhnikov E.A., Belova M.V., Evdokimova N.V., Syromyatnikova E.D., Kurilkin Yu.A. Role of intestinal translocation in the genesis of endotoxemia in acute poisoning and the detoxification effect of intestinal lavage. N.V. Sklifosovsky Journal “Emergency medical care”. 2015; (4): 16-21 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S., Badalyan A.V. Detoxification therapy of acute poisoning of chemical etiology at the present stage (lecture). Toxicological Review. 2014; (3): 9–17 (in Russian).
- Sukhodolova G.N., Luzhnikov E.A. Toxic damage of the cardiovascular system in acute poisoning in children. Moscow: Medpraktika-M, 2002 (in Russian).
- Kovalenko L.A. Sukhodolova G.N., Strakhov S.I., Simakov A.A. Problem of acute poisoning of the chemical etiology in children’s population of Moscow. Pediatrics. The journal named after G.N. Speransky. 2013; 92(5): 59-62 (in Russian).
- Badalyan A.V., Gol′dfarb Yu.S., Luzhnikov E.A., El′kov A.N., Krasilnikov A.M. Problem of rehabilitation in acute poisoning of chemical etiology. Anesthesiology and resuscitation. 2008; (6): 39-41 (in Russian).
- Luzhnikov E.A., Gol′dfarb Yu.S., Ilyashenko K.K., Badalyan A.V., Belova M.V., El′kov A.N., Matkevich V.A., etc. Rehabilitation of patients with acute poisoning: methodic. Recommendations No. 17. M.: N. V. Sklifosovsky Research Institute of SP, 2013 (in Russian).
- Matkevich V.A., Potskhveriya M.M., Gol′dfarb Yu.S., Simonova A.Yu. Violations of homeostasis parameters in acute poisoning and ways of their correction. Toxicological Review. 2018; (3, 150): 18–26 (in Russian).
- Lisovik Zh.A, Lezhenina N.F., Livanov A.S., Belova M.V., Sukhodolova G.N., Luzhnikov E.A. Use of automatic analyzers in the diagnosis of acute poisoning with medicinal and narcotic drugs. Toxicological Review. 2005; (2): 2-5 (in Russian).
- Luzhnikov E.A., Muromov A.L. Specialized care for acute poisoning. In: Fundamentals of the organization of emergency specialized medical care: a guide for doctors / ed. by B.D. Komarov. M.: Meditsina, 1986; (10): 235-247 (in Russian).
- Ostapenko Yu.N. Diagnosis and treatment of acute poisonings in the prehospital phase (lecture). M.: Central Order of Lenin Institute for Advanced Medical Studies, 1989 (in Russian).
- Ostapenko Yu.N., Dzhanelidze R.S., Litvinov N.N. Organization of the work centers (offices) of acute poisoning in the introduction of modern diagnostic, therapeutic, and information technologies: method. instructions No. 2003/57; State contract with the Ministry of Health of the Russian Federation No. 977-D of 19.12.2002. Moscow: Ministry of Health of the Russian Federation, ICTC; 2003 (in Russian).
- Goldin M.M., Luzhnikov E.A., Gol′dfarb Yu.S., Matyushkin V.A., Zimina L.N., etc. Electrochemically controlled hemosorption detoxification. Anesthesiology and resuscitation. 1998; (6): 12-15 (in Russian).
- Method of detoxification of the body. Goldin M.M., Gol′dfarb Yu.S., Kudryavtsev V.N., Kurilkin Yu.A., Kurchev I.N., Luzhnikov E.A., Martynov A.K., Musselius S.G., Naida N.N., Sergienko V.I., Labelkov M.M. Pat. RF No. 2133611. Prior. from 22.06.98 on the application for the invention No. 2133611; Op. 27.07.99 (in Russian).
- Goldin M. M., Blanchard G.J., Evseev A.K., Kolesnikov V.A., Gol′dfarb Yu.S., Volkov A.G., Goldin M. M. Redox potential (ORP) measurement in aqueous solutions and biological media. / The 212th Electrochemical Society Meeting, Washington DC, October 7-12, 2007; Abs. 0815.
- Badalyan A.V., Gol′dfarb Yu.S., El′kov A.N., Bitkova E.E., Borovkova N.V., Klychnikova E.V. Use of factor analysis to assess the effectiveness of treatment of acute poisoning at the rehabilitation stage. Toxicological Review. 2017; (6): 17–30 (in Russian).
- Badalyan A.V.,Gol′dfarb Yu.S., Potskhveriya M.M., Godkov M.A., El′kov A.N., Bitkova E.E., etc. Using cluster analysis to evaluate the effectiveness of rehabilitation treatment of acute poisoning. Toxicological Review. 2018; 3(150): 2-17 (in Russian).
- Ostapenko Yu.N. System of toxicological information and its use in the elimination of the consequences of emergency situations. In: Bonitenko Yu.Yu., Nikiforov A.M. Emergency situations of chemical nature (chemical accidents, mass poisoning; medical aspects). St. Petersburg: Hippocrates, 2004: 223-248 (in Russian).
- Prostakishin G.P., Vorontsov I.V., Gol′dfarb Yu.S., Luzhnikov E.A., Ostapenko Yu.N., etc. Organization of medical support of the population in case of chemical accidents: manual. M.: Protection; 2004 (in Russian).
- Prostakishin G.P., Gol′dfarb Yu.S., Ostapenko Yu.N., Sarmanaev S.H., Gaziyev G.A., Akhmetov R.I. Emergency medical help if inhaled lesions of toxic substances: a training manual for doctors. M.: Protection; 2017 (in Russian).
- Luzhnikov E.A., Kabanova S.A., Gol′dfarb Yu.S.., Bogopolsky P.M., Ostapenko Yu.N., Matkevich V.A., Belova M.V. On the periodization of the history of clinical toxicology in the Russian Federation. Toxicological Review. 2015; (5): 2-9 (in Russian).
- Luzhnikov E.A., Kostomarova L.G. Acute poisoning: a guide for doctors. 2nd ed., reprint. Moscow: Meditsina, 2000 (in Russian).
- Urgent therapy of acute poisoning and endotoxicosis: A reference book (ed. by E.A. Luzhnikov). Moscow: Meditsina, 2001 (in Russian).
- Luzhnikov E.A. (ed.) Emergency clinical toxicology (a guide for doctors). M.: Medpraktika-M; 2007 (in Russian).
- Luzhnikov E.A., Sukhodolova G.N. Pediatric clinical toxicology. Rostov-on-Don: Feniks; 2013 (in Russian).
- Luzhnikov E.A. Medical toxicology: national leadership. M.: GEOTAR-Media; 2012 (in Russian).
- Khubutiya M.Sh., Gol′dfarb Yu.S., Kabanov S.A., Bogopolskiy P.M., Potskhveriya M.M. Formation and development of the scientific school of academician E.A. Luzhnikov. N.V. Sklifosovsky Journal “Emergency medical care”. 2017; 6(3): 271-279 (in Russian).
- Petrikov S.S., Gol′dfarb Yu.S., Kabanova S.A. Scientific schools of the N.V. Sklifosovsky Research Institute of Emergency Medicine (in Russian).
- Lezhenina N.F.,Gol′dfarb Yu.S., Ostapenko Yu.N., Astanina S.Yu., Strakhov S.I., Sukhodolova G.N., etc. Educational role of scientific and practical activities in “Toxicology”. Pedagogy of professional medical education: a scientific and methodological electronic journal. 2019; (1). – URL: http://www.profmedobr.ru/articles/obuchajushhaja-rol-nauchno-prakticheskih-meroprijatij-po-specialnosti-toksikologija/ Accessed 14.12.2020 (in Russian).
Supplementary files
