Email this article COMPARATIVE ASSESSMENT OF INVESTIGATIONS INTO TOXIC PROPERTIES OF NANOMATERIALS IN VIVO AND IN VITRO EXPERIMENTS
- Authors: Guskova O.A.1,2, Zavyalov N.V.2, Skvorcova E.L.2, Khamidulina K.K.1,3
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Affiliations:
- State Budgetary Educational Institution of Higher Professional Education «Russian Medical Academy for Post-Graduate Education»
- Federal Budgetary Health Institution «hygienic and Epidemiological Center in the City of Moscow»
- Federal Budgetary Health Institution «Russian Register of Potentially Hazardous Chemical and Biological Substances», Rospotrebnadzor
- Issue: No 1 (2015)
- Pages: 22-28
- Section: Articles
- Published: 04.02.2015
- URL: https://vestnik.nvsu.ru/0869-7922/article/view/641291
- DOI: https://doi.org/10.15690/vramn433
- ID: 641291
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Abstract
The article presents results of studies on general toxic and irritant action of nanoscale particles of silver, zinc and titanium dioxide in experiments on animals and alternative models ( livestock sperm, Ecolum bacteria and vessels of chick embryo chorioallantoic membrane). Efficiency of using high sensitive alternative models is substantiated for screening assessment of general toxic and irritant action at the preliminary stage of general toxicological and irritant action investigations into nanoscale products .
About the authors
Oksana Albertovna Guskova
State Budgetary Educational Institution of Higher Professional Education «Russian Medical Academy for Post-GraduateEducation»; Federal Budgetary Health Institution «hygienic and Epidemiological Center in the City of Moscow»
Author for correspondence.
Email: hitrovanka@rambler.ru
Аспирант кафедры общей и коммунальной гигиены, гигиены питания и медицины труда ГБОУ ДПО РМАПО Минздрава РФ, г. Москва
e-mail: hitrovanka@rambler.ru
Russian FederationNikolay Vsevolodovich Zavyalov
Federal Budgetary Health Institution «hygienic and Epidemiological Center in the City of Moscow»
Email: nik-zav@mail.ru
Кандидат медицинских наук, зав. отделом профилактической токсикологии и санитарно-эпидемиологической экспертизы непродовольственной продукции ФБУЗ «Центр гигиены и эпидемиологии в городе Москве», г. Москва
e-mail: nik-zav@mail.ru
Russian FederationEkaterina Lvovna Skvorcova
Federal Budgetary Health Institution «hygienic and Epidemiological Center in the City of Moscow»
Email: hitrovanka@rambler.ru
Кандидат медицинских наук, зав. отделением санитарно-токсикологической и гигиенической экспертизы ФБУЗ «Центр гигиены и эпидемиологии в городе Москве», г. Москва
e-mail: hitrovanka@rambler.ru
Russian FederationKhalidia Khizbulaevna Khamidulina
State Budgetary Educational Institution of Higher Professional Education «Russian Medical Academy for Post-GraduateEducation»; Federal Budgetary Health Institution «Russian Register of Potentially Hazardous Chemical and Biological
Substances», Rospotrebnadzor
Email: khalidiya@yandex.ru
Доктор медицинских наук, профессор, заведующая кафедрой общей, коммунальной гигиены, медицины труда и гигиены питания ГБОУ ДПО РМАПО Минздрава России, директор ФБУЗ «Российский регистр потенциально
опасных химических и биологических веществ» Роспотребнадзора, г. Москва
e-mail: khalidiya@yandex.ru
Russian FederationReferences
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