Email this article MATERIALS FOR SUBSTANTIATION OF HYGIENIC STANDARDS FOR BIS (TRIPHENYLSILYL)CHROMATE IN VARIOUS ENVIRONMENTAL MEDIA
- Authors: Bidevkina M.V.1, Ivanov N.G.2, Guglja E.B.2, Skrjabina J.G.2, Sheina N.I.2
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Affiliations:
- Federal Budgetary Science Institution «Scientific Research Disinfectology Institute», Rospotrebnadzor
- State Budgetary Educational Institution of Higher Professional Education «N.I. Pirogov Russian National Research Medical University»
- Issue: No 1 (2015)
- Pages: 46-50
- Section: Articles
- Published: 04.02.2015
- URL: https://vestnik.nvsu.ru/0869-7922/article/view/641326
- DOI: https://doi.org/10.15690/vramn438
- ID: 641326
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Abstract
In experiments on white rats, the main toxicometric parameters of bis(triphenylsilyl) chromate were established at single and repeated stomach and intraperitoneal administration. The character of the biological action of bis(triphenylsilyl) chromate with different delivery paths into the organism and levels of effective doses/concentrations are analogous to those of hexavalent chromium compounds. Based on these conclusions, TLV/TWA (Threshold limit value/time-weighted average)) of bis(triphenylsilyl) chromate in occupational air, tentative safe exposure level (TSEL) in atmospheric air of residential settings, tentative permissible levels (TPL) in water of water reservoirs were substantiated and approved at the level of magnitudes adopted for hexavalent chromium compounds in RF.
About the authors
Marina Vasil’evna Bidevkina
Federal Budgetary Science Institution «Scientific Research Disinfectology Institute», Rospotrebnadzor
Author for correspondence.
Email: noemail@neicon.ru
Кандидат медицинских наук, заведующая лаборатории токсикологии дезинфекционных средств ФБУН «Научно-исследовательский институт дезинфектологии» Роспотребнадзора, 117246, г. Москва,
e-mail: BidevkinaMV@niid.ru
Russian FederationNikolaj Georgievich Ivanov
State Budgetary Educational Institution of Higher Professional Education «N.I. Pirogov Russian National Research MedicalUniversity»
Email: noemail@neicon.ru
Доктор медицинских наук, профессор, заведующий отделом токсикологии НИИФПБИ (фундаментальных и прикладных биомедицинских исследований) РНИМУ им. Н.И. Пирогова, 117997, г. Москва
Russian FederationElena Borisovna Guglja
State Budgetary Educational Institution of Higher Professional Education «N.I. Pirogov Russian National Research MedicalUniversity»
Email: noemail@neicon.ru
Кандидат химических наук, старший научный сотрудник отдела токсикологии НИИФПБИ (фундаментальных и прикладных биомедицинских исследований) РНИМУ им. Н.И. Пирогова, 117997, г. Москва
e-mail: let@rsmu.ru
Russian FederationJemilija Grigor’evna Skrjabina
State Budgetary Educational Institution of Higher Professional Education «N.I. Pirogov Russian National Research MedicalUniversity»
Email: noemail@neicon.ru
Кандидат медицинских наук, старший научный сотрудник отдела токсикологии НИИФПБИ (фундаментальных и прикладных биомедицинских исследований) РНИМУ им. Н.И. Пирогова, 117997, г. Москва
e-mail: let@rsmu.ru
Russian FederationNatalia Ivanovna Sheina
State Budgetary Educational Institution of Higher Professional Education «N.I. Pirogov Russian National Research MedicalUniversity»
Email: noemail@neicon.ru
Доктор биологических наук, доцент, профессор кафедры гигиены ГБОУ ВПО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова», 117997, г. Москва
e-mail: let@rsmu.ru
Russian FederationReferences
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