New opportunities for effective identification of unknown toxicological patients (a case from practice)

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Abstract

Introduction. The article considers the issues of identification of unknown patients admitted to toxicological medical hospitals on the example of a case from practice. The aim of the study was to develop an effective way to solve the main problem of the lack of information about the identity of a significant part of patients with a toxicological profile during their stay in the hospital until discharge.

Material and methods. Based on the described practical case, a new highly effective method of identifying unknown patients with a toxicological profile, implemented using forensic DNA analysis, is proposed and tested.

Results. As promising ways to improve interdepartmental cooperation in relation to the identification of unidentified living persons who have been admitted with acute poisoning, an algorithm for transmitting selected DNA samples to the territorial bodies of the Ministry of Internal Affairs on a system streaming basis is described.

Limitations. Further verification of DNA samples according to the Federal Database of Genomic Information is carried out by the Ministry of Internal Affairs independently through the regional Forensic Centers of the Ministry of Internal Affairs of the Russian Federation, followed by informing the administration of the medical institution.

Conclusion. The results obtained within the framework of this study demonstrate the high efficiency of establishing the identity of toxicological patients staying in medical hospitals as unknown persons, which represents a direct economic benefit for the healthcare system in the form of an increase in the proportion of patients paid for by territorial health insurance funds.

Compliance with ethical standards. The study did not require the approval of the Ethics committee.

Author contribution:
Kuznetsov S.V. — concept and design of the study, collection and processing of material, statistical processing, writing the text, editing;
Lodyagin A.N. — concept and design of the study, writing the text, editing; 
Batotsyrenov B.V., Reinuk V.L. — concept and design of the study, editing;
Sinenchenko A.G. — concept and design of the study, writing the text;
Litvincev B.S. — concept and design of the study;
Kuznetsova A.A. — collection and processing of material, writing the text;
Kirsanova N.A. — statistical processing.
All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version. 

Conflict of interest. Authors acknowledge that there are no known conflicts of interest related to this publication.

Acknowledgments. The study was not sponsored.

Received: January 22, 2023 / Accepted: July 29, 2023 / Published: August 30, 2023

About the authors

Semyon Valerevich Kuznetsov

Federal State Budgetary Institution «Scientific and Clinical Center of Toxicology named after Academician S.N. Golikov of the Federal Medical and Biological Agency of Russia»; Law faculty of the Federal State Budgetary Educational Institution of Higher Education «Saint-Petersburg State Agrarian University»

Author for correspondence.
Email: nachsml@mail.ru
ORCID iD: 0000-0002-3132-8522

PhD, associate professor, leading researcher of the Federal State Budgetary Institution «Scientific and Clinical Center of Toxicology named after Academician S.N. Golikov of the Federal Medical and Biological Agency of Russia», 192019, Saint-Petersburg; associate professor of the Law faculty of the Federal State Budgetary Educational Institution of Higher Education «Saint-Petersburg State Agrarian University», 196601, Saint-Petersburg.

e-mail: nachsml@mail.ru

Russian Federation

Aleksei Nikolaevich Lodyagin

State Budgetary Institution of Saint-Petersburg «Research Institute of Ambulance named I.I. Dzhanelidze»

Email: alodyagin@mail.ru
ORCID iD: 0000-0002-8672-2906

Доктор медицинских наук, доцент, руководитель отдела клинической токсикологии ГБУ СПб НИИ скорой помощи им. И.И. Джанелидзе, 192242, Санкт-Петербург, Россия.

e-mail: alodyagin@mail.ru

Russian Federation

Bair Vasil’evich Batotsyrenov

State Budgetary Institution of Saint-Petersburg «Research Institute of Ambulance named I.I. Dzhanelidze»

Email: bbair@mail.ru
ORCID iD: 0000-0003-4954-8977

Доктор медицинских наук, доцент, главный научный сотрудник отдела клинической токсикологии ГБУ СПб НИИ скорой помощи им. И.И. Джанелидзе, 192242, Санкт-Петербург, Россия.

e-mail: bbair@mail.ru

Russian Federation

Vladimir Leonidovich Reinuk

Federal State Budgetary Institution «Scientific and Clinical Center of Toxicology named after Academician S.N. Golikov of the Federal Medical and Biological Agency of Russia»

Email: institute@toxicology.ru
ORCID iD: 0000-0002-4472-6546

Доктор медицинских наук, доцент, Врио директора ФГБУ «Научно-клинический центр токсикологии имени академика С.Н. Голикова ФМБА России», 192019, Санкт-Петербург, Россия.

e-mail: institute@toxicology.ru

Russian Federation

Andrej Georgievich Sinenchenko

State Budgetary Institution of Saint-Petersburg «Research Institute of Ambulance named I.I. Dzhanelidze»

Email: andreysin2013@yandex.ru
ORCID iD: 0000-0003-2815-3108

Кандидат медицинских наук, руководитель отдела неотложной психиатрии, наркологии и психореабилитации ГБУ СПб НИИ скорой помощи им. И.И. Джанелидзе, 192242, Санкт-Петербург, Россия.

e-mail: andreysin2013@yandex.ru

Russian Federation

Bogdan Sergeevich Litvincev

Federal State Budgetary Institution «Scientific and Clinical Center of Toxicology named after Academician S.N. Golikov of the Federal Medical and Biological Agency of Russia»

Email: noemail@neicon.ru
ORCID iD: 0000-0001-6364-2391

Доктор медицинских наук, главный врач специализированного клинико-диагностического комплекса ФГБУ «Научно-клинический центр токсикологии имени академика С.Н. Голикова ФМБА России», 192019, Санкт-Петербург, Россия.

e-mail: institute@toxicology.ru

Russian Federation

Alexandra Alexandrovna Kuznetsova

State Public Healthcare Institution of the Leningrad region «Bureau of forensic medical examination»

Email: alexandra88@yandex.ru
ORCID iD: 0000-0002-8414-9763

Врач — судебно-медицинский эксперт I квалификационной категории, врач — судебно-медицинский эксперт отдела комплексных экспертиз ГКУЗ ЛО «Бюро судебно-медицинской экспертизы», 197198, Санкт-Петербург, Россия.

e-mail: alexandra88@yandex.ru

Russian Federation

Nadezhda Anatol’evna Kirsanova

Federal State Budgetary Institution «Scientific and Clinical Center of Toxicology named after Academician S.N. Golikov of the Federal Medical and Biological Agency of Russia»

Email: noemail@neicon.ru
ORCID iD: 0009-0009-2027-9823

Врач-статистик специализированного клинико-диагностического комплекса ФГБУ «Научно-клинический центр токсикологии имени академика С.Н. Голикова ФМБА России», 192019, Санкт-Петербург, Россия.

e-mail: institute@toxicology.ru

Russian Federation

References

  1. Federal Law of the Russian Federation No. 242-FZ of 03.12.2008 “On State Genomic Registration in the Russian Federation” [Federal`ny`j zakon Rossijskoj Federacii ot 03.12.2008 № 242-FZ «O gosudarstvennoj genomnoj registracii v Rossijskoj Federacii»]. URL: https://base.garant.ru/12163758/89300effb84a59912210b23abe10a68f (accessed: 11.01.2023). (in Russian)
  2. Order of the Ministry of Internal Affairs of Russia No. 70 dated 10.02.2006 “On the organization of the use of forensic records of internal affairs bodies of the Russian Federation” [Prikaz MVD Rossii ot 10.02.2006 № 70 «Ob organizacii ispol’zovanija jekspertno-kriminalisticheskih uchetov organov vnutrennih del Rossijskoj Federacii»]. URL: https://base .garant.ru/72222630 (accessed: 11.01.2023). (in Russian)
  3. Order of the Ministry of Health of the Russian Federation No. 664n dated 24.06.2021 “On approval of the Procedure for informing medical organizations of internal affairs bodies in cases established by paragraph 5 of Part 4 of Article 13 of the Federal Law “On the Basics of Public Health Protection in the Russian Federation” [Prikaz Ministerstva zdravoohranenija Rossijskoj Federacii ot 24.06.2021 № 664n «Ob utverzhdenii Porjadka informirovanija medicinskimi organizacijami organov vnutrennih del v sluchajah, ustanovlennyh punktom 5 chasti 4 stat’i 13 Federal’nogo zakona “Ob osnovah ohrany zdorov’ja grazhdan v Rossijskoj Federacii”»]. URL: https://www.garant.ru/products/ipo/prime/doc/402537218 (accessed: 11.01.2023). (in Russian)

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Copyright (c) 2023 Kuznetsov S.V., Lodyagin A.N., Batotsyrenov B.V., Reinuk V.L., Sinenchenko A.G., Litvincev B.S., Kuznetsova A.A., Kirsanova N.A.



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