Enviar artigo por via de e-mail ACUTE TOXICITY OF THE MINERAL COMPLEX BASED ON NANOPOWDERS OF IRON, COPPER AND ZINC AFTER A SINGLE INTRAPERITONEAL INJECTION
- Autores: Andreeva E.Y.1, Rodionova T.N.1, Gorbunov D.V.2, Marinicheva M.P.1
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Afiliações:
- N.I. Vavilov Saratov State Agrarian University.
- Institute of Toxicology of the Federal Medical and Biological Agency.
- Edição: Nº 6 (2018)
- Páginas: 22-24
- Seção: Articles
- ##submission.datePublished##: 28.12.2018
- URL: https://vestnik.nvsu.ru/0869-7922/article/view/641133
- DOI: https://doi.org/10.36946/0869-7922-2018-6-22-24
- ID: 641133
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Resumo
An injection form of the mineral complex consisting of a mixture of iron, zinc and copper nanopowders has been proposed. According to the results of studies the injection form of the drug based on metal nanopowders belongs to the V-VI class of practically non-toxic, relatively harmless drugs by Hodge and to the 5th class of toxicity in accordance with GOST 32644-2014.
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Sobre autores
E. Andreeva
N.I. Vavilov Saratov State Agrarian University.
Autor responsável pela correspondência
Email: fake@neicon.ru
410012, Saratov. Rússia
T. Rodionova
N.I. Vavilov Saratov State Agrarian University.
Email: fake@neicon.ru
410012, Saratov. Rússia
D. Gorbunov
Institute of Toxicology of the Federal Medical and Biological Agency.
Email: fake@neicon.ru
192019, Saint-Petersburg. Rússia
M. Marinicheva
N.I. Vavilov Saratov State Agrarian University.
Email: fake@neicon.ru
410012, Saratov. Rússia
Bibliografia
- Polyanskaya I.S. New classification of bioelements in bioelementology. Milk herald. 2014; 1: 34-41. (in Russian)
- Alyautdin R.N., Romanov B.K. Recommendations for the evaluation of the safety of drugs containing nanoparticles. Safety and risk of pharmacotherapy. 2015; 5: 10-21. (in Russian)
- Guidelines for conducting preclinical studies of drugs. Part one. Edited by Mironov A.N. - M .: Grief and K, 20- 944 p. (in Russian)
- GOST 32644-2014 Test methods for the effects of chemical products on the human body. Acute oral toxicity - method for determining the class of acute toxicity, 2015. (in Russian)
- Reznichenko L.S., Dybkova S.N., Doroshenko A.M., Chekmani I.S., Ulberg Z.R. Synthesis of iron nanoparticles and characterization of their biosafety. Bulletin of problems of biology and medicine. 2014; 3 (2): 319-323. (in Russian)
- Prozorovsky V.B. Statistical processing of pharmacological research results. Psychopharmacology and biological narcology. 207 (3): 2090-2120. (in Russian
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